AIS-MACA- Z: MACA based Clonal Classifier for Splicing Site, Protein Coding and Promoter Region Identification in Eukaryotes

Authors

  • Pokkuluri Kiran Sree Department of CSE, JNTU Hyderabad, India
  • Inampudi Ramesh Babu Department of CSE, ANU, Guntur, India
  • SSSN Usha Devi N Department of CSE, University College of Engineering, JNTUK, India

Keywords:

MACA(Multiple Attractor Cellular Automata), CA(Cellular Automata), AIS (Artificial Immune System), Clonal Algorithm, AIS-MACA-Z(Artificial Immune System- Multiple Attractor Cellular Automata-Version Z)

Abstract

Bioinformatics incorporates information regarding biological data storage, accessing mechanisms and presentation of characteristics within this data. Most of the problems in bioinformatics and be addressed efficiently by computer techniques. This paper aims at building a classifier based on Multiple Attractor Cellular Automata (MACA) which uses fuzzy logic with version Z to predict splicing site, protein coding and promoter region identification in eukaryotes. It is strengthened with an artificial immune system technique (AIS), Clonal algorithm for choosing rules of best fitness. The proposed classifier can handle DNA sequences of lengths 54,108,162,252,354. This classifier gives the exact boundaries of both protein and promoter regions with an average accuracy of 90.6%. This classifier can predict the splicing site with 97% accuracy. This classifier was tested with 1, 97,000 data components which were taken from Fickett & Toung , EPDnew, and other sequences from a renowned medical university.

Author Biography

  • Pokkuluri Kiran Sree, Department of CSE, JNTU Hyderabad, India
    Sri Pokkuluri Kiran Sree received his B.Tech in Computer Science & Engineering, from J.N.T.U and M.E in Computer Science & Engineering from Anna University. He is pursuing Ph.D in Computer Science from J.N.T.U, Hyderabad. His areas of interests include Cellular Automata, Parallel Algorithms, Artificial Intelligence, and Compiler Design. He was the reviewer for many International Journals and IEEE Society Conferences on Artificial Intelligence & Image Processing. His bibliography was listed in Marquis Who’s Who in the World, 29th Edition (2012), USA. He is the recipient of Bharat Excellence Award from Dr GV Krishna Murthy, Former Election Commissioner of India.He received Active Reviewer Award for International Journal of Information Technology. He is also selected for GLORY OF EDUCATION EXCELLENCE AWARD 2012.He is the Board of Studies member of Vikrama Simhapuri University, Nellore in Computer Science & Engineering stream.

References

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Published

2014-04-03

Issue

Vol. 1 No. 1 (2014)

Section

Research Articles

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